Aspirin is proven to reduce preecclampsia risk. The optimal dose is 150 mg/day and works better if started before 16th gestational week (Start at 11-13 weeks and use till 36th GW). Optimal candidates for aspirin are:
●Previous pregnancy with preeclampsia, especially early onset and with an adverse outcome.
●Type 1 or 2 diabetes mellitus.
●Chronic hypertension.
●Multifetal gestation.
●Kidney disease.
●Autoimmune disease with potential vascular complications (antiphospholipid syndrome, systemic lupus erythematosus).